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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 18, 1988 - Issue 11
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Original Articles

An Improved Synthesis of 4-Cycloheptene-1-Carboxylic Acid

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Pages 1193-1199 | Published online: 06 Dec 2006
 

Abstract

Modification of the method of Stork and Landesman (J. Am. Chem. Soc. 1956, 78, 5129) permitted the synthesis of the title acid (1) in 58% yield from a cyclopentanone enamine. Acid 1 is a useful intermediate for the preparation of 4-substituted cycloheptenes in good yields.

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