Synthesis of Insecticidally Active 3-Phenoxy Benzyl and α (RS) Cyano-3-Phenoxy Benzyl (±) Trans 2-(2, 2-Dichlorovinyl) Spiro (2,5)-Octane-1-Carboxylates

Abstract

Cyclopropane carboxylic acid esters, possessing spirofused cycloallcyl rings, in place of the conven- tional gem-dimethyl group of natural pyrethrins and synthetic pyrethroids also exhibit good insecticidal I activity against a wide range of insect species. In addition, these compounds exhibit knock-down activity on flying insects. Someoc-cyan0-3-phenoxy benzyl esters of (±) - cis and (±) trans 2-(2,2-dichlorovinyl)-spiro (2,5)-octane-l-carboxylic acid and the lower spiro cycloalkyl members of the homologous series, have been synthesised and found to be active against, musca domestica, cotton leafworm etc, with good knock-down effect. The acid moieties of the above esters have been synthesised by reaction of alkyl diazo acetates on suitably substituted olefins 2, 3.