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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 18, 1988 - Issue 18
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Original Articles

Bnzyhatically Cleavable Alkoxycarbonyl Ethoxymethyl Esters for Reversible Blocking of Carboxyl Groups

D. Klomm Department of Chemistry, Friedrich-Sehiller-University of Jena, 6900, Jena, GDR
&
G. Gesehwend Department of Chemistry, Friedrich-Sehiller-University of Jena, 6900, Jena, GDR
Pages 2337-2348 | Published online: 03 Jan 2007
 
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Abstract

By O-alkylation carboxylix acids with α-bromo-α-ethoxy acetates new alkoxycarbonyl ethoxymethyl esters (ACEM esters) were synthetic in a simple route. The ACEM blocking group can be easily cleft by esterases.

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