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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 19, 1989 - Issue 1-2
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Original Articles

Improved Nucleophilic Displacements in N-Methyl Pyrrolidinone as a Solvent

, , , , &
Pages 179-188 | Received 18 May 1988, Published online: 24 Oct 2006
 

Abstract

The nucleophilic displacement reactions of 2- and 4- halogenonaphthalic-1,8, anhydrides and the N-imides, of 4,7- dichloroquinolines, the alkylation of lithio alkynes, the methylation of ethyl or methyl diacetylacetate and a variety of related reactions are greatly facilitated in N-methylpyrrolidinone as aprotic solvent.

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