α-Amidoalkylation of CH-Acids by Means of N-(1,2,2,2-Tetrachloroethyl)-amides

C. Ivanov Faculty of Chemistry, University of Sofia, boul. A. Ivanov 1, Sofia, 1126, Bulgaria

A. Dobrev Faculty of Chemistry, University of Sofia, boul. A. Ivanov 1, Sofia, 1126, Bulgaria

L. Nechev Faculty of Chemistry, University of Sofia, boul. A. Ivanov 1, Sofia, 1126, Bulgaria

T. Nikiforov Faculty of Chemistry, University of Sofia, boul. A. Ivanov 1, Sofia, 1126, Bulgaria

Abstract

The reaction of α-amidoalkylation of malonic and acetoacetic esters as well as tert. butylacetate, arylacetic acids and benzylcyanide with different N-(1,2,2,2-tetrachloroethyl)-amides was investigated and 2-substituted 3-acylamino-3-trichloromethyl propionic acids and esters were synthezised.

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α-Amidoalkylation of CH-Acids by Means of N-(1,2,2,2-Tetrachloroethyl)-amides

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α-Amidoalkylation of CH-Acids by Means of N-(1,2,2,2-Tetrachloroethyl)-amides

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