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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 19, 1989 - Issue 13-14
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Original Articles

Synthesis of Anthranilonitriles by Fragmentation of Isatin Oxime Triflates

James B. Campbell Jr. Medicinal Chemistry Department, ICI Pharmaceuticals Group A Business Unit of ICI Americas, Inc., Wilmington, Delaware, 19897
&
Timothy V. Davenport Medicinal Chemistry Department, ICI Pharmaceuticals Group A Business Unit of ICI Americas, Inc., Wilmington, Delaware, 19897
Pages 2255-2263 | Received 06 Mar 1989, Published online: 24 Oct 2006
 
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Abstract

Isatin oxime triflates undergo a facile fragmentation which is promoted by DBU, to form anthranilonitriles after hydrolytic work-up.

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