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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 19, 1989 - Issue 13-14
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Original Articles

A Short Synthesis of Fusaric Acid and Analogues

Adrian Waldner Central Research Laboratories, Ciba-Geigy Ltd., CH-4002, Basel, Switzerland
Pages 2371-2374 | Received 20 Mar 1989, Published online: 24 Oct 2006
 
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Abstract

Fusaric acid (5-n-butyl-pyridine-2-carboxylic acid) and other substituted picolinic acid derivatives are synthesized in two steps from readily available α,β-unsaturated hydrazones and 2-chloroacrylonitrile in high yield.

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