Synthesis of 2-Aroylimjnopyrimido[3,2-B]-1,2,4-Thiadiazolines

K. Kamala Department of Chemistry, Osmania University, Hyderabad, 500 007, India

P. Jayaprasad Rao Department of Chemistry, Osmania University, Hyderabad, 500 007, India

K. Kondal Reddy Department of Chemistry, Osmania University, Hyderabad, 500 007, India

Abstract

N-Aroyl-N′-(pyrimid-2-yl)-thioureas (2) have been synthesised by the reaction of 2-amino pyrimidines (1) with aroyl chlorides and ammonium thiocyanate in acetone- Cyclisation of 2 with PCl₅ in POCl₃ and as well as by oxidising agents gave 2-aroyHrninopyrimido[3,2-b]-1,2,4-thiadiazolines (3).

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Synthesis of 2-Aroylimjnopyrimido[3,2-B]-1,2,4-Thiadiazolines

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Synthesis of 2-Aroylimjnopyrimido[3,2-B]-1,2,4-Thiadiazolines

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