Abstract
The tricyclic antidepressant agents 11-(3-N,N-dimethyIammopropylidene)-6H, 11H-dibenzo-[p,e]-thiepin hydrochloride (Dothiepin) and 11-(3-N,N-dimethylamino-propylidene)-6H,11H-dibenzo-[b,e]oxepin hydrochloride (Doxepin) have been prepared in good yield by Grignard reactions in toluene.