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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 20, 1990 - Issue 19
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Original Articles

A Convenient Synthesis of Halogenated 2-Chloropyridines by Transformation of Halogenated 2-methoxypyridines Under Vilsmeier-Haack Conditions

Min-Jen Shiao Institute of Chemistry, Academia Sinica Nankang, Taipei, Taiwan, Republic of China
,
Li-Ming Shyu Institute of Chemistry, Academia Sinica Nankang, Taipei, Taiwan, Republic of China
,
Kai-Yih Tarng Institute of Chemistry, Academia Sinica Nankang, Taipei, Taiwan, Republic of China
&
Ying-Tsun Ma Department of Biochemistry, Taipei Medical College Taipei, Taiwan, Republic of China
Pages 2971-2977 | Received 31 Jul 1990, Published online: 24 Oct 2006
 
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Abstract

Several halogenated 2-chloropyddines 2a-2h were conveniently synthesized by transformation of halogenated 2-methoxypyridines 1a-1h under Vilsmeier—Haack conditions in a yield of 50∼71%.

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