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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 21, 1991 - Issue 14
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Original Articles

An Enzymatic Enantioselective Route to Methyl Carboxylate 2,3 - Methanohomoserine γ-Lactone; A Precursor of Chiral 2,3 - Methanohomoserine

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Pages 1429-1432 | Received 27 Mar 1991, Published online: 24 Sep 2006
 

Abstract

Enzymatic hydrolysis of Dimethyl 2 - (tetrahydropyranyl) hydroxymethyl cyclopropane 1,1 - dicarboxylate 6 with an industrial esterase, followed by a deprotection of tetrahydropyranyl ether affords the title compound in 20% yield.

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