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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 21, 1991 - Issue 14
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Original Articles

Lipase-Mediated Acylation of Acyclonucleosides. Application to Novel Fluoroquinolone Derivatives

Angeles de la Cruz Instituto de Química Médica (C.S.I.C), Juan de la Cierva, 3, 28006, Madrid
,
José Elguero Instituto de Química Médica (C.S.I.C), Juan de la Cierva, 3, 28006, Madrid
,
Vicente Gotor Departamento de Química Organometálica, Universidad de Oviedo, 33071, Oviedo
,
Pilar Goya Instituto de Química Médica (C.S.I.C), Juan de la Cierva, 3, 28006, Madrid
,
Ana Martínez Instituto de Química Médica (C.S.I.C), Juan de la Cierva, 3, 28006, Madrid
&
Francisco Moris Departamento de Química Organometálica, Universidad de Oviedo, 33071, Oviedo
Pages 1477-1480 | Received 08 Apr 1991, Published online: 24 Sep 2006
 
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Abstract

A novel kind of acyclonucleoside derived from fluoroquinolones is described. Lipases have been used to prepare acyl derivatives under mild conditions and in good yields.

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