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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 21, 1991 - Issue 15-16
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Original Articles

Concise and Efficient Synthesis of 1H-Pyrazoles: Reaction of [Hydroxy(tosyloxy)iodo]benzene with Ethyl 2,3-Dioxobutanoate-2-arylhydrazones

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Pages 1583-1588 | Received 15 Apr 1991, Published online: 23 Sep 2006
 

Abstract

Ethyl 2,3-dioxobutanoate-2-arylhydrazones 1 on treatment with [hydroxy(tosyloxy)iodo]benzene 2 at reflux temperature and followed by heating in the presence of N-ethyldiisopropylamine afforded the cyclized ethyl 1-aryl-4-hydroxy-1H-3-pyrazolecarboxylates 4 in good yield.

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