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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 21, 1991 - Issue 17
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Original Articles

A New and Convenient Reduction of Cephalosporin Sulphoxides

János Pitlik Research Group for Antibiotics of the Hungarian Academy of Sciences, Lajos Kossuth University, H-4010 Debrecen, P. O. Box 70, Hungary
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Ferenc Sztaricskai Research Group for Antibiotics of the Hungarian Academy of Sciences, Lajos Kossuth University, H-4010 Debrecen, P. O. Box 70, Hungary
Pages 1769-1776 | Received 06 May 1991, Published online: 24 Sep 2006
 
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Abstract

A new, convenient and good yield reduction of cephalosporin S (β)-sulphoxides to the corresponding sulphides was achieved upon treatment with iodotrimethylsilane (TMSI) in dichloromethane.

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