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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 22, 1992 - Issue 2
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Original Articles

Solid-Liquid Phase Transfer Catalytic Synthesis. VII The Synthesis of α-Substituted-2-pyridylmethyl-amine via the Alkylation of Benzaldehyde Imine

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Pages 265-269 | Published online: 23 Sep 2006
 

Abstract

The anion derived from the benzaldehyde imine 2 reacts with alkyl halide to form alkylated products 3; Hydrolysis of 3 gives α-alkyl-2 pyridylmethylamine in 34–53% overall yield.

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