Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 23, 1993 - Issue 4
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Original Articles

Extension of the Bobbitt Acetal Cyclization to the Elaboration of 1-Hydroxymethyl-Substituted Simple Tetrahydroisoquinolines. A New Synthesis of Calycotomine

Pages 473-486 | Received 31 Aug 1992, Published online: 23 Sep 2006
 

Abstract

Aromatic benzyloxymethyl ketones are convenient intermediates for the elaboration, via the Bobbitt acetal cyclization, of 1-hydroxymethyl-substituted simple tetrahydroisoquinolines, such as calycotomine and one bearing the 1,7,8-oxygenated substitution pattern of MY336-a.

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