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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 23, 1993 - Issue 5
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Original Articles

Bicyclo [3.3.0]Octane Derivatives for Carbaprostacyclin Synthesis

C. W. Bird Department of Chemistry, King's College, The Strand, London, WC2R 2LS, U. K.
,
E. C. J. Coffee Rhone-Poulenc Rorer, Dagenham Research Centre, Rainham Road South, Dagenham, Essex, RM10 7XS, U. K.
&
B. W. C. Schmidl Rhone-Poulenc Rorer, Dagenham Research Centre, Rainham Road South, Dagenham, Essex, RM10 7XS, U. K.
Pages 613-620 | Received 09 Sep 1992, Published online: 27 Oct 2006
 
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Abstract

Convenient syntheses of the epimeric 3-hydroxy-2α-carb-oxybicyclo[3.3.0]octane-4α,6α-carbolactones are described which commence from the readily available cyclopentadienone dimer.

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