Abstract
n-Butyllithium at −78°C abstracts the methine proton from 4-dimethoxymethylpyridine. The anion reacts efficiently with electrophiles. Simple ketal products can be readily hydrolysed to 4-pyridyl ketones.
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 23, 1993 - Issue 14
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