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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 23, 1993 - Issue 14
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Original Articles

An Efficient Synthesis of an Angiotensin II Antagonist (A-81988)

, , , , , , & show all
Pages 2027-2039 | Received 08 Feb 1993, Published online: 16 Feb 2007
 

Abstract

A new and efficient synthesis of A-81988, an angiotensin II antagonist, is described. The preparation utilizes a novel method for tetrazole formation from nitriles requiring trimethylsilyl azide and a catalytic amount of dialkyltin oxide.

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