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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 23, 1993 - Issue 17
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Original Articles

Synthesis of (Indol-3-ylmethyl)trimethylsilanes by Means of Alumina-Mediated Alkylation of Indoles with α-Chloro-α-silylsulfides

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Pages 2381-2387 | Received 13 Feb 1993, Published online: 23 Sep 2006
 

Abstract

Treatment of a mixture of indoles and α-chloro-α-silylsulfide 6 with neutral chromatographic alumina afforded the aromatic substitution products 8, which were desurfurized with Bu3SnH and AIBN to give (indol-3-ylmethyl)trimethylsilanes 9.

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