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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 24, 1994 - Issue 13
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Original Articles

A Simple One-Pot Procedure for the Synthesis of 1,3,4-Oxadiazoles

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Pages 1879-1885 | Received 09 Dec 1993, Published online: 23 Sep 2006
 

Abstract

A new method of synthesis of the 2,5-disubstituted 1,3,4-oxadiazoles, which uses the reaction of N-acyl-aldehyde hydrazones with chloramine T is described. The title compounds are obtained in very good yields (85–96%).

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