Synthesis of Functionalized 3,3,9,9-Tetramethyl-4,8-Diazaundecane-2,10-Dione Dioximes (Propylene Amine Oximes, PnAOs)

K. Ramalingam The Bristol-Myers Squibb Pharmaceutical Research Institute, P.O. Box 4000, Princeton, NJ, 08543-4000

W. Zeng The Bristol-Myers Squibb Pharmaceutical Research Institute, P.O. Box 4000, Princeton, NJ, 08543-4000

P. Nanjappan The Bristol-Myers Squibb Pharmaceutical Research Institute, P.O. Box 4000, Princeton, NJ, 08543-4000

D. P. Nowotnik The Bristol-Myers Squibb Pharmaceutical Research Institute, P.O. Box 4000, Princeton, NJ, 08543-4000

Abstract

The syntheses of several new derivatives of PnAO and their chloronitroso precursors are described. The PnAOs were prepared by an improvement of the reported general procedure. An unexpected product, an isooxalone, was formed while attempting to prepare 1-carbomethoxyl-PnAO.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Synthesis of Functionalized 3,3,9,9-Tetramethyl-4,8-Diazaundecane-2,10-Dione Dioximes (Propylene Amine Oximes, PnAOs)

Information for

Open access

Opportunities

Help and information

Synthesis of Functionalized 3,3,9,9-Tetramethyl-4,8-Diazaundecane-2,10-Dione Dioximes (Propylene Amine Oximes, PnAOs)

Abstract

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature