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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 25, 1995 - Issue 19
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Original Articles

Alkylation and Hydrolysis of Phenylacetonitriles Under Microwave Irradiation

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Pages 3007-3013 | Received 03 Feb 1995, Published online: 16 Feb 2007
 

Abstract

Alkylation of phenylacetonitriles is performed by solid-liquid phase transfer catalysis in 1–3 minutes under microwave irradiation (one hour with a two-phase system). These nitriles can be quickly hydrolysed in a microwave oven to yield the corresponding amides or acids according to the reaction time.

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