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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 25, 1995 - Issue 23
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Original Articles

An Efficient Synthesis of 2,8-Diazabicyclo[4.3.0]-nonane Derivatives via Intramolecular Cyclization Reaction

Jae Wook Lee R&D Center, Dae Woong Pharmaceutical Co., LTD., 223-23 Sangdaewondong, Sungnam, Kyunggi-Do, 462-120, Korea
,
Ho Jung Son R&D Center, Dae Woong Pharmaceutical Co., LTD., 223-23 Sangdaewondong, Sungnam, Kyunggi-Do, 462-120, Korea
,
Jae Ho Lee R&D Center, Dae Woong Pharmaceutical Co., LTD., 223-23 Sangdaewondong, Sungnam, Kyunggi-Do, 462-120, Korea
,
Yeon Eui Jung R&D Center, Dae Woong Pharmaceutical Co., LTD., 223-23 Sangdaewondong, Sungnam, Kyunggi-Do, 462-120, Korea
,
Geal Jung Yoon R&D Center, Dae Woong Pharmaceutical Co., LTD., 223-23 Sangdaewondong, Sungnam, Kyunggi-Do, 462-120, Korea
&
Myung Hwan Park R&D Center, Dae Woong Pharmaceutical Co., LTD., 223-23 Sangdaewondong, Sungnam, Kyunggi-Do, 462-120, Korea
Pages 3741-3746 | Received 19 Apr 1995, Published online: 23 Sep 2006
 
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Abstract

Novel 5-functionalized-2,8-diazabicyclo[4.3.0]nonane derivatives 5 were synthesized from epoxide 1 through 4 steps in 46.7∼52.6% yield.

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