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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 25, 1995 - Issue 6
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Original Articles

4-Substituted 2-Phenyl- and 2-Phenyl-3-Aryl Pyrroles by Reaction of Tosyl Benzyl Isocyanide (TosBIC) with Michael Acceptors

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Pages 795-802 | Received 08 Aug 1994, Published online: 23 Sep 2006
 

Abstract

Synthesis of 2-phenyl and 2,3-diphenylpyrroles bearing at the 4 position electronwithdrawing groups by reaction of tosylbenzylisocyanide (TosBIC) with various Michael acceptors was investigated. Sodium hydride and n-butyllithium were used as deprotonating agents for the synthesis of monophenyl and diphenylpyrroles, respectively.

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