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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 25, 1995 - Issue 14
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Original Articles

A Mild Method for the Cleavage of Si-C Bond in Oligonucleotide Synthesis

Vasulinga T. Ravikumar Isis Pharmaceuticals 2292 Faraday Avenue, Carlsbad, CA, 92008
Pages 2161-2164 | Received 01 Dec 1994, Published online: 23 Sep 2006
 
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Abstract

A mild and convenient method for the cleavage of silyl-carbon bonds in oligonucleotides using tetrafluorosilane in acetonitrile is described.

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