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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 25, 1995 - Issue 14
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Original Articles

Improved Syntheses of Peptide Coupling Reagents Bop and PyBOP Using Triphosgene

I. A. Rivero Centro de Graduados e Investigación del Instituto Tecnológico de Tijuana, Apdo. Postal 1166, 22000, Tijuana, B.C., México
,
R. Somanathan Centro de Graduados e Investigación del Instituto Tecnológico de Tijuana, Apdo. Postal 1166, 22000, Tijuana, B.C., México
&
L. H. Hellberg Centro de Graduados e Investigación del Instituto Tecnológico de Tijuana, Apdo. Postal 1166, 22000, Tijuana, B.C., México
Pages 2185-2188 | Received 01 Dec 1994, Published online: 23 Sep 2006
 
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Abstract

Synthesis of Benzotriazolyloxy tris [dimethyl-amino] phosphonium hexafluorophosphate (BOP) and Benzotriazolyloxy tris [pyrrolidino] phosphonium hexafluorophosphate (PyBOP), using triphosgene and hydroxybenzotriazole.

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