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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 26, 1996 - Issue 7
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Original Articles

A Facile One Stage Synthesis of Oxazolines Under Microwave Irradiation

David S. Clarke Cardiovascular and Metabolism Department, Zeneca Pharmaceuticals, Alderley Park, Macclesfield, Cheshire, SK10 4TG., U.K.
&
Robin Wood Cardiovascular and Metabolism Department, Zeneca Pharmaceuticals, Alderley Park, Macclesfield, Cheshire, SK10 4TG., U.K.
Pages 1335-1340 | Received 15 Sep 1995, Published online: 15 Aug 2006
 
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Abstract

A rapid, high yielding procedure for the synthesis of 2-substituted oxazolines has been achieved under microwave irradiation from alkyl and aryl nitriles and β-amino alcohols using a mild Lewis acid catalyst.

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