N-Alkylation of Amino Acid Esters Using Sodium Triacetoxyborohydride: Synthetic Communications: Vol 26, No 7

Synthetic Communications

An International Journal for Rapid Communication of Synthetic Organic Chemistry

Volume 26, 1996 - Issue 7

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Abstract

N-Alkylation of amino acid esters by reductive amination using sodium cyanoborohydride may often be problematic. Sodium triacetoxyborohydride was found to be a convenient reagent for this transformation. This methodology was employed to alkylate various amino acid methyl esters.

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N-Alkylation of Amino Acid Esters Using Sodium Triacetoxyborohydride

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N-Alkylation of Amino Acid Esters Using Sodium Triacetoxyborohydride

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