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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 26, 1996 - Issue 7
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Original Articles

A Novel Synthetic Route to Dihydro- and α-Hydroxytetrahydro-furan Derivatives

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Pages 1385-1399 | Received 30 Sep 1995, Published online: 15 Aug 2006
 

Abstract

1-(3-Morpholinoprop-2-enyl)benzotriazole (1) provides a three carbon unit for the construction of dihydro- and tetrahydro-furan rings by one pot procedures. Lithiation of 1 followed by reaction with diaryl ketones gave 2,5-dihydro- and/or α-hydroxytetrahydro-furans, whereas successive reactions with iodoalkanes and diaryl ketones yielded 2,3-dihydrofurans.

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