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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 26, 1996 - Issue 11
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Original Articles

Lewis Acid Mediated Addition of Tri-n-Butylstannylmethylisoxazole with Aldehydes

Makoto Yamamoto Department of Materials Science, Faculty of Engineering, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba-shi, 263, Japan
,
Kazumi Ohtsuka Department of Materials Science, Faculty of Engineering, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba-shi, 263, Japan
,
Keiki Kishikawa Department of Materials Science, Faculty of Engineering, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba-shi, 263, Japan
&
Shigeo Kohmoto Department of Materials Science, Faculty of Engineering, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba-shi, 263, Japan
Pages 2177-2187 | Received 18 Sep 1995, Published online: 21 Aug 2006
 
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Abstract

Lewis acid mediated addition of 5-(tri-n-butylstannyl)methyl-3-methylisoxazole and its analogues with aldehydes have been carried out. Corresponding 5-(β-hydroxy)ethylisoxazoles were obtained in moderate yields, without ring opening of the isoxazole.

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