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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 26, 1996 - Issue 3
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Original Articles

Studies Directed Toward the Synthesis of Macrolactins: Asymmetric Synthesis of C3-C9 and C17-C24 Subunits of Macrolactin A

Shinji Tanimori Department of Applied Biochemistry, College of Agriculture, Osaka Prefecture University, 1–1 Gakuen-cho, Sakai, Osaka, 593, JAPAN
,
Yuuji Morita Department of Applied Biochemistry, College of Agriculture, Osaka Prefecture University, 1–1 Gakuen-cho, Sakai, Osaka, 593, JAPAN
,
Masakazu Tsubota Department of Applied Biochemistry, College of Agriculture, Osaka Prefecture University, 1–1 Gakuen-cho, Sakai, Osaka, 593, JAPAN
&
Mitsuru Nakayama Department of Applied Biochemistry, College of Agriculture, Osaka Prefecture University, 1–1 Gakuen-cho, Sakai, Osaka, 593, JAPAN
Pages 559-567 | Received 22 May 1995, Published online: 21 Aug 2006
 
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Abstract

C3-C9 and C17-C24 subunits (2 and 3) of marine macrolide macrolactin A (1) were synthesized starting from known diol 5 and methyl (R)-3-hydroxybutylate 9 as chiral starting materials by straightforward manner.

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