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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 26, 1996 - Issue 23
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Original Articles

Synthesis of 3-methyl-7-[2-(dimethylaminoethyl)oximino]-5-arylcyclopenta [F] Benzoxazolinones, Potential Ligands of the 5HT1D Receptors

Didier Varlet Laboratoire de Chimie Thérapeutique, Faculté des Sciences Pharmaceutiques et Biologiques, 3, rue du Professeur Laguesse, BP 83 59006, Lille, cedex, France
,
Patrick Depreux Laboratoire de Chimie Thérapeutique, Faculté des Sciences Pharmaceutiques et Biologiques, 3, rue du Professeur Laguesse, BP 83 59006, Lille, cedex, France; Société ADIR, 1, rue Carle Hébert, 92145, Courbevoie, Cedex, France
,
Isabelle Lesieur Laboratoire de Chimie Thérapeutique, Faculté des Sciences Pharmaceutiques et Biologiques, 3, rue du Professeur Laguesse, BP 83 59006, Lille, cedex, France
&
Bruno Pfeiffer Société ADIR, 1, rue Carle Hébert, 92145, Courbevoie, Cedex, France
Pages 4319-4328 | Received 15 Mar 1996, Published online: 23 Aug 2006
 
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Abstract

The synthesis of 3-methyl-7-[2-(dimethylaminoethyl)oximino]-5-arylcyclopenta [f] benzoxa-zolinones, potential ligands of the 5HT1D receptors is described through a 4 steps reaction strategy from 3-methyl-6-acetyl benzoxazolinone.

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