Intramolecular Cyclization Reactions of N-Alkylaryl-and N, N-Dialkylarylureas with Aldehydes

Abstract

The reactions of N-alkylaryl-and N, N′-dialkylarylureas with aldehydes in acidic medium leads to the synthesis of N-carbamoyltetrahydro-isoquinolines and tetrahydro-1,3,5-oxadiazin-4-ones (urons) depending on the structure of starting compounds and the reaction conditions.