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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 26, 1996 - Issue 17
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Original Articles

A Convenient, Large-Scale Preparation of a Differentially Protected α-Aminoglycine Suitable for the Synthesis of α-Aminoglycine-Containing Peptides

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Pages 3237-3239 | Received 23 Feb 1996, Published online: 21 Aug 2006
 

Abstract

α-Boc-amino-Fmoc-glycine 6 was prepared in two steps from 9-fluorenyl-methylcarbamate 1, glyoxylic acid 3 and t-butyl carbamate 5. This compound is useful in Solid Phase Peptide Synthesis to prepare α-aminoglycine-containing peptides using Fmoc-strategy.

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