New Synthesis of Some Isothiazol and 1,2,4-Dithiazol Derivatives

Abstract

treatment of 3-anilino thiocinnamic acid anilides 1 with trifluoromethylsulfenyl chloride 3 leads to intramolecular cyclisation of 1 resulting in isothiazol system 4 with excellent yields. Anilides of 3-oxothioacids 2 react with 3 to give 1,2,4-dithiazol derivative 5, product of intermolecular cyclisation. Physical data of the novel compounds are reported.