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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 26, 1996 - Issue 4
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Original Articles

A Convenient one-pot synthesis of n-arylmalonamic acid via in-situ generation of malonyl monoacyl chloride

Hsiencheng Shih Department of Pharmacology School of Medicine, Marsall University, Huntington, WV, 25755-9310
&
Gary O Rankin Department of Pharmacology School of Medicine, Marsall University, Huntington, WV, 25755-9310
Pages 833-836 | Received 19 Jul 1995, Published online: 21 Nov 2007
 
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Abstract

A convenient one-pot synthesis of N-arylmalonamic acid has been demonstrated based on the in-situ generation ofmalonyl monoacyl chloride, followed by reaction with aniline.

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