Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 27, 1997 - Issue 14
98
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Original Articles

Friedel-Crafts Cyclization of N,N-dibenzylethylenediamines

Pages 2533-2538 | Received 09 Jan 1997, Published online: 21 Aug 2006
 

Abstract

An efficient synthesis of substituted 1,2,3,4-tetrahydro-isoquinolines is described. N,N-dibenzylethylenediamines smoothly under go Friedel-Crafts cyclization in the presence of anhydrous aluminum chloride in decalin to give 1,2,3,4-tetrahydroisoquinolines.

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