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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 27, 1997 - Issue 16
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Original Articles

A Convenient Synthesis of 3- and 3,4-Substituted 4,5-Dihydroisoxazole-5-Acetic Acids

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Pages 2733-2742 | Received 27 Jan 1997, Published online: 22 Aug 2006
 

Abstract

The 4,5-dihydroisoxazole-5-acetic acids 4a-j were prepared from the ketoximes 1a-j, 2,2-dimethyl-5-methoxymethylene-1,3-dioxan-4,6-dione (2) and butyllithium in yields from 35 to 79%.

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