A Rapid and Efficient Preparation of Linear and Macrocyclic Polyamine Bolaphiles

Abstract

The preparation of linear polyamine bolaphiles via a highly efficient and rapid synthetic strategy avoiding column chromatography is described. Cyclization of these compounds affords a ready access to macrocyclic polyamine bolaphiles. This approach represents a significant improvement over the original synthetic protocol.

Current Address: Drexel University, Dept of Chemistry, Philadelphia, PA 19104; [email protected]

Notes

Current Address: Drexel University, Dept of Chemistry, Philadelphia, PA 19104; [email protected]