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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 27, 1997 - Issue 16
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Original Articles

Chlorotrimethylsilane - A Novel Catalyst in Friedel-Crafts Reaction

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Pages 2877-2883 | Received 27 Mar 1997, Published online: 22 Aug 2006
 

Abstract

In the Friedel-Crafts condensation of diaryl carbinol with substituted phenols, the use of chlorotrimethylsilane (CTMS) as catalyst, leads to the formation of triarylmethanes under mild conditions. 6-Methoxy-1,2,3,4-tetrahydronaphthalen-1-ol under similar condition, on condensation with o-cresol, gives 1-(4-hydroxy-3-methyl phenyl)-6-methoxy-1,2,3,4-tetrahydronaphthalene.

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