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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 27, 1997 - Issue 20
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Original Articles

A Simple and Convenient Method for the Synthesis of Nitriles by Oxidation of Primary Amines with NaOCl in Ethanol

Shigekazu Yamazaki Toyama Industrial Technology Center, 150 Futagami, Takaoka, Toyama, 933, Japan
Pages 3559-3564 | Received 20 Feb 1997, Published online: 22 Aug 2006
 
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Abstract

The oxidation of aliphatic primary amines having α-methylene on treatment with NaOCl as an oxidant in ethanol has been found to be an effective method for the transformation of primary amines to nitriles.

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