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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 28, 1998 - Issue 23
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Original Articles

Tetramethylammonium Hydrogendifluoride: A Convenient Source of Nucleophilic Fluoride

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Pages 4295-4301 | Received 01 Jun 1998, Published online: 23 Aug 2006
 

Abstract

Tetramethylammonium hydrogendifluoride (TMAHF2) acts as an effective fluoride source for the selective fluorination in high yields of various chloro and nitroaromatics via halogen exchange (halex) and fluorodenitration.

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