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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 28, 1998 - Issue 23
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Original Articles

Synthesis of 8-Halopurines by Reaction of Lithiated Purines with Appropriate Halogen Donors

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Pages 4303-4315 | Published online: 23 Aug 2006
 

Abstract

Purines lithiated in the 8-position, can be trapped with hexachloroethane, dibromotetrachloroethane, cyanogen bromide and cyanogen iodide, to give a variety of 8-halopurines in excellent yields.

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