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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 28, 1998 - Issue 23
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Original Articles

Unsymmetrically Substituted Aliphatic Diacetylenes Containing Amine Functionalities

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Pages 4333-4338 | Received 01 Jun 1998, Published online: 23 Aug 2006
 

Abstract

A one-pot reaction which combines the Cadiot-Chodkiewicz coupling reaction with the Gabriel synthesis of primary amines is evaluated as a means for the synthesis of unsymmetrically disubstituted aminodiacetylenes of the type CH2-(CH2)n-C≡C-C≡C-CH2-NH2 (n=2,3,4,5).

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