Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 28, 1998 - Issue 23
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Original Articles

A Facile Route to 9-Phosphorylated Neuraminic Acid Derivatives

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Pages 4393-4400 | Received 01 Jun 1998, Published online: 23 Aug 2006
 

Abstract

The phosphitylation of 2-α-O-Benzyl-N-acetylneuraminic acid (2) and of the methyl 2-α-O-methyl-N-acetylneuraminate (3) with 2-chloro-4H-1,2,3-benzodioxaphosphorin-4-one (4) is described. The reaction affords a ready access to 9-phosphorylated derivatives of N-acetylneuraminic acid (1).

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