Abstract
A catalytic and efficient oxidative coupling of thiols to disulfides is described using Cu(NO3)2.N2O4 as a new and efficient nitrosating agent in acetone at room temperature. The reaction is shown to occur immediately through the intermediacy of a thionitrite.
Notes
The reaction was performed between 1,3 propanedithiol (2 mmol) and Cu(NO3)2, N2O4 (0.4 mmol) in acetone (200 ml) at room temperature. After 8 h, the product was isolated according to the procedure and identified by its 1H, 13C-NMR and mass spectra data.