Sterically Hindered Phenanthrolines: Synthesis Of 1,7,7-Trimethyl[2.2.1]Bicycloheptano-[2,3-B]-L,10-Phenanthroline From (+)-Camphor

Abstract

The title compound was prepared in 51 % overall yield through a three step reaction sequence starting from 8-nitro-7-quinolinecarbaldehyde and (+)-camphor. This route offers a useful alternative to the Friedlander reaction which provides only a 5% yield of the title compound.