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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 29, 1999 - Issue 10
349
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Original Articles

Direct Esterification Of Poly (Ethylene Glycol) With Amino Acid Hydrochlorides

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Pages 1727-1739 | Received 06 May 1998, Published online: 17 Sep 2007
 

Abstract

Diesters of poly (ethylene glycol) with various a amino acid hydrochlorides were synthesized using dicyclohexyl carbodiimide as coupling agent. The use of hydrochloride as amino protecting group in dicyclohexyl carbodiimide mediated condensation reactions of amino acids was demonstrated for the first time.

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