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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 29, 1999 - Issue 10
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Original Articles

Thionyl Chloride-Benzotriazole: An Efficient System For Transformation Of Aldoximes to Nitriles

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Pages 1741-1745 | Received 14 Nov 1998, Published online: 17 Sep 2007
 

Abstract

Dehydration of aromatic as well as aliphatic aldoximes using thionyl chloride-benzotriazole combination in dry DCM proceeds smoothly at room temperature to give the corresponding nitriles in high yields (>90%) in shorter time(~20min).

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